stoufferMeta - Weighted meta-analysis of p-values via Stouffer’s method

Description¶

stoufferMeta combines multiple weighted p-values into a meta-analysis p-value using Stouffer’s Z-score method.

Usage¶

stoufferMeta(p, w = NULL)

Arguments¶

p

numeric vector of p-values.

w

numeric vector of weights.

Value¶

A named numeric vector with the combined Z-score and p-value in the form c(Z, pvalue).

Examples¶

# Define p-value and weight vectors
p <- c(0.1, 0.05, 0.3)
w <- c(5, 10, 1)

# Unweighted
stoufferMeta(p)

         Z     pvalue 
1.99232360 0.02316778 

# Weighted
stoufferMeta(p, w)

         Z     pvalue 
2.08291783 0.01862936